CRI-SPA: a high-throughput method for systematic genetic editing of yeast libraries
Graphical abstract. Taken from the original publication: https://doi.org/10.1093/nar/gkad656Abstract
This came from one of the collaborations I worked on during my postdoc. The paper presents CRI-SPA, an experimental method for transferring chromosomal genetic features from a donor strain to large libraries of S. cerevisiae. The method is highly efficient, reproducible and scalable, and is promising for systems-level understanding of cellular processes. I was involved in the first implementation of the method, at the data analysis level.
Type
Publication
Nucleic acids research
