Genome-scale metabolic modeling of P. thermoglucosidasius NCIMB 11955 reveals metabolic bottlenecks in anaerobic metabolism
Overview of reactions in model. Taken from the original publication: https://doi.org/10.1016/j.ymben.2021.03.002Abstract
This came from one of the collaborations I worked on during my postdoc. I had the privilege to supervise Viviënne while she built from scratch a metabolic genome-scale model of P. thermoglucosidasius, a thermophilic facultative anaerobic bacterium. The model was developed using the principles we established in a previous publication, and was extensively curated and validated. It was used to predict carbon utilization, and identify minimal required supplemented nutrients in medium so that the organism can grow. It was a fun project that we mainly worked on remotely during the COVID-19 pandemic.
Type
Publication
Metabolic Engineering
